Preheat the oven to 325 degrees F. Spray two 8-inch cake pans with nonstick spray, line the bottom with parchment paper and spray again. Set aside.
In the bowl of an electric mixer, stir together the dry ingredients.
In a separate medium size mixing bowl, whisk together the eggs, buttermilk, water, oil and vanilla.
With the mixer on low speed, slowly add the wet ingredients to the dry ingredients. Batter will be thin. Scrape sides and mix for another 30 seconds. Divide batter evenly among prepared pans.
Bake for 30-35 minutes (you may need more time depending on your oven), until toothpick comes out almost clean. Cool on wire racks for 10-15 minutes, then gently invert onto racks until cooled completely.
When cakes are completely cooled, I like to wrap each cake layer individually with plastic wrap and stick it in the refrigerator or freezer until I’m ready to frost. The cake will be easier to work with if it’s cooled a bit. If I’m making the cake a day or two before I actually need to frost it, I put it in the freezer to ensure freshness. If I’m frosting same-day, I’ll just put it in the refrigerator to chill until needed.